A Prospective Evaluation of the Microfracture Technique

Lesions in the Knee. A Prospective Cohort Study The Microfracture Technique for the Treatment of Articular Cartilage

Articular cartilage treatment in high-level male soccer players: a prospective comparative study of arthroscopic second-generation autologous chondrocyte implantation versus microfracture.

BACKGROUND Soccer is a highly demanding sport for the knee joint, and chondral injuries can cause disabling symptoms that may jeopardize an athlete's career. Articular cartilage lesions are difficult to treat, and the increased mechanical stress produced by this sport makes their management even more complex. HYPOTHESIS To evaluate whether the regenerative cell-based approach allows these hig...

A novel, minimally-invasive technique of cartilage repair in the human knee using arthroscopic microfracture and injections of mesenchymal stem cells and hyaluronic acid--a prospective comparative study on safety and short-term efficacy.

INTRODUCTION Most current cell-based cartilage repair techniques require some form of scaffolds and 2 separate surgical procedures. We propose a novel, scaffold-less technique of cartilage repair in the human knee that combines arthroscopic microfracture and outpatient intra-articular injections of autologous bone marrow-derived mesenchymal stem cells (MSCs) and hyaluronic acid (HA). MATERIAL...

Matrix-Applied Characterized Autologous Cultured Chondrocytes Versus Microfracture: Five-Year Follow-up of a Prospective Randomized Trial.

BACKGROUND Matrix-based cell therapy improves surgical handling, increases patient comfort, and allows for expanded indications with better reliability within the knee joint. Five-year efficacy and safety of autologous cultured chondrocytes on porcine collagen membrane (MACI) versus microfracture for treating cartilage defects have not yet been reported from any randomized controlled clinical t...

Microfracture in Football (Soccer) Players

Background: Little information is available on the results of microfracture in competitive football (soccer) players. We aimed to evaluate the efficacy of this technique to restore joint function to a level that allows return to this popular highimpact sport. Methods: This article provides an overview of the basic science and the current published scientific evidence for articular cartilage rep...